Skip to content
#

pole

Here are 15 public repositories matching this topic...

Research framework for POLE c.138del (p.Leu46Phefs*8) — an ultra-rare frameshift variant causing PPAP with ultra-hypermutated tumor phenotype (TMB >100 mut/Mb). Mechanistic models, therapeutic strategies, and experimental priorities.

  • Updated Apr 19, 2026
  • TeX

Improve this page

Add a description, image, and links to the pole topic page so that developers can more easily learn about it.

Curate this topic

Add this topic to your repo

To associate your repository with the pole topic, visit your repo's landing page and select "manage topics."

Learn more